Which of the following statements are correct with regards to anaphylaxis? (Select 2 correct answers)

a. Prostaglandins are a key mediator in anaphylaxis as they cause vasodilation, increased vascular permeability, and smooth muscle contraction.

b. Anaphylaxis is a severe allergic reaction that can be fatal.

c. Cytokines are a key mediator in anaphylaxis as they cause vasodilation, increased vascular permeability, and smooth muscle contraction.

d. Anaphylaxis refers to a death following a poison which results in cardiovascular compromise.

e. Anaphylaxis can be the result of a toxin which causes fatal symptoms.

f. Anaphylaxis does not occur the first time a person is exposed to an allergen as you first need to be sensitised.

g. Histamine is a key mediator in anaphylaxis as it causes vasodilation, increased vascular permeability, and smooth muscle contraction.



Answer :

Final answer:

Anaphylaxis involves key mediators like prostaglandins and histamine causing severe allergic reactions with potentially fatal outcomes.


Explanation:

Correct statements regarding anaphylaxis:

  1. Prostaglandins are a key mediator in anaphylaxis, causing vasodilation, increased vascular permeability, and smooth muscle contraction.
  2. Anaphylaxis is a severe allergic reaction that can be fatal.
  3. Cytokines are not a key mediator in anaphylaxis.
  4. Histamine is a key mediator in anaphylaxis, causing vasodilation, increased vascular permeability, and smooth muscle contraction.

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