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Based on 2020 data from the Gonococcal Isolate Surveillance Project (GISP), which one of the following is an accurate estimate of the rate of Neisseria gonorrhoeae antimicrobial resistance?

A. Approximately 4% of isolates had elevated ceftriaxone MICs (≥0.125 μg/mL)
B. Approximately 7% of isolates had elevated cefixime MICs (≥0.25 μg/mL)
C. Approximately 18% of isolates had elevated azithromycin MICs (≥2.0 μg/mL)
D. Approximately 20% of isolates were resistant to tetracycline



Answer :

GinnyAnswer
To determine the accurate estimate of the rate of Neisseria gonorrhoeae antimicrobial resistance based on the provided options and the data from 2020, let's analyze each of the given statements:

1. Approximately 4% of isolates had elevated ceftriaxone MICs (20.125 μg/mL).
2. Approximately 7% of isolates had elevated cefixime MICs (20.25 μg/mL).
3. Approximately 18% of isolates had elevated azithromycin MICs (22.0 μg/mL).
4. Approximately 20% of isolates were resistant to tetracycline.

The correct rate of resistance based on 2020 data is the percentage given in option 4: 20% of isolates were resistant to tetracycline.

This means, in the year 2020, among the surveillance data collected, approximately 20% of Neisseria gonorrhoeae isolates were found to be resistant to tetracycline. The other options (4%, 7%, and 18% for ceftriaxone, cefixime, and azithromycin, respectively) are not the correct estimates based on the provided data.

So the final answer is:

Approximately 20% of isolates were resistant to tetracycline.

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