Answer :
To determine the sequence of nucleotides in the template strand of DNA that codes for the polypeptide sequence Phe-Ser-Gin, follow these steps:
1. Identify the Codons: We know that the peptide sequence Phe-Ser-Gin corresponds to the mRNA codons UUC, UCU, and CAA. This is directly from the problem statement.
2. Determine the Complementary DNA Sequence:
- In mRNA, the bases pair with their complementary bases during transcription to form the template DNA strand:
- Adenine (A) pairs with Thymine (T) in DNA.
- Uracil (U) in RNA pairs with Adenine (A) in DNA.
- Cytosine (C) pairs with Guanine (G).
- Guanine (G) pairs with Cytosine (C).
Using these base pairing rules, convert each mRNA codon to its corresponding DNA template sequence:
- UUC (mRNA) -> AAG (DNA)
- UCU (mRNA) -> AGA (DNA)
- CAA (mRNA) -> GTT (DNA)
3. Combine the Template DNA Sequences: Now put these individual DNA sequences together to form the complete template strand sequence:
- AAG-AGA-GTT
So, the sequence of nucleotides in the template strand of DNA that could code for the polypeptide sequence Phe-Ser-Gin is:
AAG-AGA-GTT
1. Identify the Codons: We know that the peptide sequence Phe-Ser-Gin corresponds to the mRNA codons UUC, UCU, and CAA. This is directly from the problem statement.
2. Determine the Complementary DNA Sequence:
- In mRNA, the bases pair with their complementary bases during transcription to form the template DNA strand:
- Adenine (A) pairs with Thymine (T) in DNA.
- Uracil (U) in RNA pairs with Adenine (A) in DNA.
- Cytosine (C) pairs with Guanine (G).
- Guanine (G) pairs with Cytosine (C).
Using these base pairing rules, convert each mRNA codon to its corresponding DNA template sequence:
- UUC (mRNA) -> AAG (DNA)
- UCU (mRNA) -> AGA (DNA)
- CAA (mRNA) -> GTT (DNA)
3. Combine the Template DNA Sequences: Now put these individual DNA sequences together to form the complete template strand sequence:
- AAG-AGA-GTT
So, the sequence of nucleotides in the template strand of DNA that could code for the polypeptide sequence Phe-Ser-Gin is:
AAG-AGA-GTT