Clostridium difficile produces toxins that cause antibiotic-associated colitis with severe symptoms.
Clostridium difficile is a Gram-positive bacterium that produces two toxins, toxin A (TcdA) and toxin B (TcdB), which play a crucial role in causing antibiotic-associated colitis. These toxins lead to actin condensation, cell death, and can progress to pseudomembranous colitis, causing severe symptoms like watery diarrhea, fever, and abdominal pain.
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