Which postoperative medication is administered to promote peristalsis?
A. Ketorolac
B. Lorazepam
C. Hydromorphone
D. Metoclopramide



Answer :

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Answer:

Option D, metoclopramide


Explanation:

The antiemetic medication metoclopramide (brand name Reglan) is primarily used in the treatment of gastric reflux and post-operative nausea and vomiting prophylaxis. However, because of its ability to stimulate upper gastrointestinal (GI) motility thereby decreasing gastric stasis, it is also used to promote peristalsis. The administration of sedatives (e.g. propofol), opioids, and other medications used pre- and intraoperatively can halt normal peristaltic activity in the GI system.

In laymen's terms, this drug can be the stomach's 'on' switch so that it can once again begin chemically breaking down ingested material and involuntarily moving content into the intestines to become fecal matter after the drugs given during procedure interrupted the normal wave-like flow.

Lorazepam (a benzodiazepine medication, brand name Ativan) and hydromorphone (an opioid medication, brand name Dilaudid) are both known to cause constipation, the direct opposite of the desired effect. Ketorolac (a nonopioid analgesic, brand name Toradol) can cause diarrhea as a common side effect, which would be the result of GI hyperactivity.

Thus, option D, metoclopramide, would be administered postoperatively to promote peristalsis.

D. Metoclopramide is the postoperative medication administered to promote peristalsis.


This medication promote peristalsis and alleviate symptoms of ileus, a condition where normal bowel movements are impaired after surgery. It acts as a prokinetic agent by stimulating the motility of the upper gastrointestinal tract.

Specifically, metoclopramide enhances the coordination and strength of contractions in the stomach and small intestine, which helps move food, fluids, and gas through the digestive system.

This action not only prevents or reduces the likelihood of postoperative ileus but also aids in restoring normal gastrointestinal function, facilitating early recovery and oral intake after surgery.