Answered

\begin{tabular}{|l|l|}
\hline
Antibiotic Disc & Psa \\
\cline{2-2}
& ZI \\
\hline
Penicillin P & 0 \\
\hline
Sulfadiazine SD & 0 \\
\hline
Polymyxin B PB & 15 \\
\hline
Streptomycin S & 8 \\
\hline
\end{tabular}

Based on the data shown above, which of the antibiotics would you prescribe to a patient infected with this strain of Pseudomonas aeruginosa?

\begin{tabular}{|l|l|l|l|}
\hline
Antibiotic & Resistant (R) & Intermediate (I) & Sensitive (S) \\
\hline
Penicillin & [tex]$\leq 28$[/tex] & - & [tex]$\geq 29$[/tex] \\
\hline
Sulfadiazine & [tex]$\leq 12$[/tex] & 13-16 & [tex]$\geq 17$[/tex] \\
\hline
Polymyxin B & [tex]$\leq 8$[/tex] & 9-11 & [tex]$\geq 12$[/tex] \\
\hline
Streptomycin & [tex]$\leq 11$[/tex] & 12-14 & [tex]$\geq 15$[/tex] \\
\hline
\end{tabular}

A. Streptomycin
B. Sulfadiazine
C. Polymyxin B
D. None of these
E. Penicillin



Answer :

To determine which antibiotic should be prescribed for a patient infected with this strain of Pseudomonas aeruginosa, we need to compare the zone of inhibition (ZI) values for each antibiotic against the sensitivity thresholds provided.

Here is the detailed step-by-step analysis:

1. Penicillin P:
- Given ZI: 0
- Sensitivity threshold: 229
- Since 0 is significantly less than 229, Penicillin P is not effective against this strain.

2. Sulfadiazine SD:
- Given ZI: 0
- Sensitivity threshold: 217
- Since 0 is significantly less than 217, Sulfadiazine SD is not effective against this strain.

3. Polymyxin B PB:
- Given ZI: 15
- Sensitivity threshold: 212
- Since 15 is significantly less than 212, Polymyxin B PB is not effective against this strain.

4. Streptomycin S:
- Given ZI: 8
- Sensitivity threshold: 215
- Since 8 is significantly less than 215, Streptomycin S is not effective against this strain.

Based on the given sensitivity thresholds and zone of inhibition values for the antibiotics tested against this strain of Pseudomonas aeruginosa, none of the antibiotics (Penicillin P, Sulfadiazine SD, Polymyxin B PB, Streptomycin S) are effective. Therefore, given the choices:

- Streptomycin
- Sulfadiazine
- Polymyxin B
- None of these
- Penicillin

The correct answer is:

None of these