Gram-positive and Gram-negative bacteria exhibit structural differences that impact their chemical resistance capabilities.
Gram-positive bacteria have thick layers of peptidoglycan and teichoic acids in their cell walls, while Gram-negative bacteria have a thinner cell wall with an outer membrane containing lipopolysaccharides (LPS). These structural differences contribute to the chemical resistance variations between the two organisms. For example, the presence of LPS in Gram-negative bacteria acts as an endotoxin, which can be harmful to the host.
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