The process in which a transplant recipient's immune system attacks the transplanted organ or tissue is called:

A. graft-versus-host disease
B. graft elimination
C. disseminated intravascular coagulation
D. graft rejection
E. viscerogenic



Answer :

Final answer:

Graft rejection and graft-versus-host disease (GVHD) are rejection processes in organ transplants triggered by the recipient's immune response against donor tissue, involving immune cells targeting foreign cells.


Explanation:

Graft rejection occurs when the recipient's immune system views the transplanted organ or tissue as foreign, triggering an immune response. This rejection process involves the recognition of non-self molecules by the host's dendritic cells, activating cytotoxic T cells that target and kill the grafted cells.

Graft-versus-host disease (GVHD) is a type of rejection where donor T cells from the transplanted tissue attack the recipient's cells, leading to acute GVHD. This is a significant concern in bone marrow transplants due to the immune response mounted by the transplanted tissue.

Major histocompatibility complex markers (MHC I and MHC II), also known as human leukocyte antigens (HLAs), play a crucial role in transplant rejection by triggering the recipient's immune response against the donor tissue.


Learn more about organ transplant rejection here:

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