Let's analyze the given matrix to determine if there is a discernable pattern or relationship between the numbers in order to fill in the missing element.
The given matrix is:
| | |
|-------|-------|
| -2 | +44 |
| -3 | 16 |
| 8 | +4 |
| 64 | |
We are asked to fill in the missing number.
However, without any additional context or a specific rule, we can't determine the relationship between the numbers in the two columns. As such, there is no clear way to calculate the last missing number in the table based on the given values.
Therefore, with the current information provided, the answer is indeterminable.
So, the final answer is:
- The number in the missing place can't be determined based on the given information.