West Africans were chosen over Native Americans for enslaved labor due to disease resistance and immunity to European diseases.
West Africans were preferred over native people of the Americas for enslaved labor due to their resistance to tropical diseases and their experience with agriculture and tropical climates. Additionally, by 1600, Africans had developed immunity to European diseases, making them more viable as a labor source compared to the indigenous populations that were decimated by diseases brought by Europeans.
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