Vancomycin prevents the incorporation of NAG and NAM into bacterial cell walls by binding to cell wall precursors.
Vancomycin, a glycopeptide antibiotic, blocks the incorporation of N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) into the peptidoglycan structure of bacterial cell walls. It does this by binding to the end of the peptide chain of cell wall precursors, inhibiting transglycosylation, and also blocking transpeptidation.
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