The lectin pathway for complement action is initiated by mannose-binding lectin and microbial carbohydrates, assisting in defense against infections.
The lectin pathway for complement action is initiated by mannose-binding lectin (MBL) or ficolins found in plasma and tissue fluids. This pathway is triggered by the binding of microbial carbohydrates, specifically mannose, on the pathogen's surface to MBL.
MBL functions as an opsonin, assisting in the attachment of microorganisms to phagocytes, and then activates the lectin pathway. This pathway, similar to the classical pathway, helps in defense against infections by activating the complement proteins.
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