QUESTION 3

Match the pathogen to its virulence factor:

1. Streptococcus pyogenes
2. Corynebacterium diphtheriae
3. Klebsiella pneumoniae
4. Bordetella pertussis
5. Mycobacterium tuberculosis

A. endotoxin and fimbriae
B. endotoxin and capsule
C. AB exotoxin
D. prevents formation of the phagolysosome
E. M protein

[0.5 points]

Virulence factors of specific pathogens include the M protein in Streptococcus, mycolic acid in Mycobacterium tuberculosis, and the AB exotoxin in Bordatella pertussis.

Explanation:

Streptococcus pyogenes produces the M protein as a virulence factor which inhibits phagocytosis by blocking complement molecules.

Mycobacterium tuberculosis produces mycolic acid in its cell envelope, allowing it to resist killing mechanisms within phagolysosomes.

Bordatella pertussis produces an AB exotoxin as a virulence factor.

Learn more about Microbial virulence factors here:

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