Final answer:
Hemoglobin recycling primarily occurs in the liver and spleen through a complex process involving the breakdown of red blood cells and heme components.
Explanation:
Hemoglobin is recycled by macrophages primarily in the liver and spleen.
Red blood cells are broken down in these organs, with iron recovered and reused. The heme in hemoglobin is processed into bilirubin in the liver and then excreted into the gastrointestinal tract.
Additionally, globin from hemoglobin is broken down into amino acids, and any non-iron portions of heme are converted into waste products like biliverdin, bilirubin, and eventually eliminated as stercobilin in feces.
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