How would the removal of calcium ions from a blood sample affect coagulation?

A. Coagulation would occur only in Rh positive individuals.
B. There would be no important effect because magnesium can substitute for calcium.
C. Coagulation would be prevented.
D. More blood cells would be produced.
E. The coagulation pathway would be more sensitive to activation.

Removal of calcium ions from a blood sample prevents coagulation as calcium is essential for clotting, leading to the use of anticoagulants like oxalates and citrates.

Explanation:

Removal of calcium ions from a blood sample affects coagulation by preventing it. Calcium ions are crucial for clotting, and their absence hinders the blood from coagulating, leading to a prevention of coagulation. Substances like oxalates, citrates, and EDTA are used as anticoagulants because they precipitate calcium into insoluble salts, thereby preventing blood clotting.

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