Louis Pasteur's major contribution to biology was disproving spontaneous generation and establishing the Germ Theory of disease, transforming medicine.
Louis Pasteur made a major contribution to biology by determining that organisms do not spontaneously generate, providing evidence for the Germ Theory of disease. This discovery revolutionized medicine by showing that microbes were responsible for causing disease, leading to the development of pasteurization and vaccines against diseases like anthrax.
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