Answer :
Final answer:
Depression, Ineffective coping, and Caregiver role strain are appropriate differential nursing diagnoses for the single mother based on her symptoms.
Explanation:
Depression, Ineffective coping, and Caregiver role strain would be appropriate differential nursing diagnoses for the 45-year-old single mother described. She exhibits signs of emotional distress, lack of coping mechanisms, and strain related to her caregiving responsibilities for her child with Down syndrome. These diagnoses are based on the symptoms of feeling worthless, fatigue, malaise, and lack of interest in social activities, reflecting a possible depressive episode.
Learn more about Depression and caregiving stress here:
https://brainly.com/question/42732353