Which differential nursing diagnosis would be appropriate for a 45-year-old single mother living with her 10-year-old son with Down syndrome who presents to the clinic with an unkempt appearance, facial expressions and manners demonstrating fatigue and malaise, and no interest in going out and meeting people, who states, "I feel worthless and am overburdened with my responsibilities"?

Select all that apply. One, some, or all responses may be correct.

A. Anemia
B. Psychosis
C. Depression
D. Ineffective coping
E. Caregiver role strain

Depression, Ineffective coping, and Caregiver role strain would be appropriate differential nursing diagnoses for the 45-year-old single mother described. She exhibits signs of emotional distress, lack of coping mechanisms, and strain related to her caregiving responsibilities for her child with Down syndrome. These diagnoses are based on the symptoms of feeling worthless, fatigue, malaise, and lack of interest in social activities, reflecting a possible depressive episode.

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