Answer :
To classify the types of mutations that occurred in the given sequences, we first need to understand the potential mutation types and compare the original sequence to each changed sequence.
1. Original Sequence: CATTCACACA
2. Changed Sequences:
- CATTCACACCACG
- CATTTCACACG
- CATTCACG
- CATTGCACAC
Let's analyze each changed sequence against the original one to determine the type of mutation.
### 1. Sequence: CATTCACACCACG
Comparison:
- Original: CATTCACACA
- Changed: CATTCACACCACG
Observation:
- The changed sequence has additional nucleotides at the end compared to the original.
Mutation Type:
- Insertion: Extra nucleotides (CCACG) are added to the original sequence.
### 2. Sequence: CATTTCACACG
Comparison:
- Original: CATTCACACA
- Changed: CATTTCACACG
Observation:
- The nucleotide 'A' is replaced with 'T' in the third position of the sequence.
Mutation Type:
- Substitution: 'A' is replaced by 'T' in the position 3.
### 3. Sequence: CATTCACG
Comparison:
- Original: CATTCACACA
- Changed: CATTCACG
Observation:
- The changed sequence is shorter than the original, with some nucleotides missing.
Mutation Type:
- Deletion: "ACA" (the last part of the original sequence) is deleted.
### 4. Sequence: CATTGCACAC
Comparison:
- Original: CATTCACACA
- Changed: CATTGCACAC
Observation:
- The nucleotide 'C' is replaced with 'G' in the sixth position of the sequence.
Mutation Type:
- Substitution: 'C' is replaced by 'G' in the position 6.
### Filling in the Table
[tex]\[ \begin{array}{|c|c|c|} \hline \text{Type of Mutation} & \text{Original Nucleotide Sequence} & \text{Changed Nucleotide Sequence} \\ \hline \text{insertion} & \text{CATTCACACA} & \text{CATTCACACCACG} \\ \hline \text{substitution} & \text{CATTCACACA} & \text{CATTTCACACG} \\ \hline \text{deletion} & \text{CATTCACACA} & \text{CATTCACG} \\ \hline \text{substitution} & \text{CATTCACACA} & \text{CATTGCACAC} \\ \hline \text{inversion} & \text{CATTCACACA} & \text{} \\ \hline \text{duplication} & \text{CATTCACACA} & \text{} \\ \hline \end{array} \][/tex]
Note that there are no examples of inversion or duplication in the given sequences.
1. Original Sequence: CATTCACACA
2. Changed Sequences:
- CATTCACACCACG
- CATTTCACACG
- CATTCACG
- CATTGCACAC
Let's analyze each changed sequence against the original one to determine the type of mutation.
### 1. Sequence: CATTCACACCACG
Comparison:
- Original: CATTCACACA
- Changed: CATTCACACCACG
Observation:
- The changed sequence has additional nucleotides at the end compared to the original.
Mutation Type:
- Insertion: Extra nucleotides (CCACG) are added to the original sequence.
### 2. Sequence: CATTTCACACG
Comparison:
- Original: CATTCACACA
- Changed: CATTTCACACG
Observation:
- The nucleotide 'A' is replaced with 'T' in the third position of the sequence.
Mutation Type:
- Substitution: 'A' is replaced by 'T' in the position 3.
### 3. Sequence: CATTCACG
Comparison:
- Original: CATTCACACA
- Changed: CATTCACG
Observation:
- The changed sequence is shorter than the original, with some nucleotides missing.
Mutation Type:
- Deletion: "ACA" (the last part of the original sequence) is deleted.
### 4. Sequence: CATTGCACAC
Comparison:
- Original: CATTCACACA
- Changed: CATTGCACAC
Observation:
- The nucleotide 'C' is replaced with 'G' in the sixth position of the sequence.
Mutation Type:
- Substitution: 'C' is replaced by 'G' in the position 6.
### Filling in the Table
[tex]\[ \begin{array}{|c|c|c|} \hline \text{Type of Mutation} & \text{Original Nucleotide Sequence} & \text{Changed Nucleotide Sequence} \\ \hline \text{insertion} & \text{CATTCACACA} & \text{CATTCACACCACG} \\ \hline \text{substitution} & \text{CATTCACACA} & \text{CATTTCACACG} \\ \hline \text{deletion} & \text{CATTCACACA} & \text{CATTCACG} \\ \hline \text{substitution} & \text{CATTCACACA} & \text{CATTGCACAC} \\ \hline \text{inversion} & \text{CATTCACACA} & \text{} \\ \hline \text{duplication} & \text{CATTCACACA} & \text{} \\ \hline \end{array} \][/tex]
Note that there are no examples of inversion or duplication in the given sequences.