Sickle cell anemia is caused by a mutation in the hemoglobin gene, altering the shape of red blood cells and impacting oxygen delivery in the body.
In sickle cell anemia, a single point mutation in the gene for hemoglobin causes a change in the amino acid sequence of the protein. This mutation leads to the formation of long fibers that distort red blood cells, causing them to assume a sickle shape, which can result in serious health issues such as blockages in blood vessels. The mutation affects the structure and function of hemoglobin, disrupting oxygen delivery in the body.
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