Agammaglobulinemia and Severe Combined Immunodeficiency result in lack of adaptive immunity due to deficient B and/or T cells, while Selective IgA deficiency involves a specific immunoglobulin deficiency without affecting B or T cells.
Agammaglobulinemia and Severe Combined Immunodeficiency are genetic diseases that result in almost no adaptive immunity due to the lack of B and/or T cells. Selective IgA deficiency, on the other hand, affects the production of secretory IgA but does not involve a lack of B or T cells.
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