Which of the following genetic immunodeficiencies involve B cells?

A. Selective immunoglobulin A deficiency, agammaglobulinemia, and severe combined immunodeficiency
B. DiGeorge syndrome, selective immunoglobulin A deficiency, and HIV/AIDS
C. DiGeorge syndrome, severe combined immunodeficiency, and chronic granulomatous disease
D. DiGeorge syndrome, selective immunoglobulin A deficiency, and agammaglobulinemia
E. Selective immunoglobulin A deficiency, severe combined immunodeficiency, and HIV/AIDS



Answer :

Final answer:

Agammaglobulinemia and Severe Combined Immunodeficiency result in lack of adaptive immunity due to deficient B and/or T cells, while Selective IgA deficiency involves a specific immunoglobulin deficiency without affecting B or T cells.


Explanation:

Agammaglobulinemia and Severe Combined Immunodeficiency are genetic diseases that result in almost no adaptive immunity due to the lack of B and/or T cells. Selective IgA deficiency, on the other hand, affects the production of secretory IgA but does not involve a lack of B or T cells.


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