Answer :

Final answer:

Cocaine use can lead to loss of smell (anosmia) as a long-term health effect.


Explanation:

Loss of smell, known as anosmia, can be a long-term health effect of using cocaine. Cocaine, when taken through regular intranasal use (snorting), can lead to loss of the sense of smell among other adverse effects like nosebleeds and hoarseness.


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