Rh factor incompatibility can result in hemolytic disease of the newborn, causing destruction of fetal red blood cells.
Rh factor incompatibility between mother and fetus can lead to a condition known as hemolytic disease of the newborn (HDN), also called erythroblastosis fetalis. In this condition, if an Rh-negative mother carries an Rh-positive fetus, the mother's antibodies can destroy the fetal red blood cells, leading to anemia and potentially severe outcomes for the newborn.
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