Loop diuretics inhibit reabsorption of Na+ and Cl- ions in the loop of Henle, leading to increased urine production, aiding in hypertension treatment.
Loop diuretics are drugs that inhibit the reabsorption of Na+ and Cl- ions in the ascending limb of the loop of Henle. This inhibition leads to increased urine production, which is a desired effect in treating conditions like hypertension. The increased urination helps reduce fluid volume and thus decreases blood pressure.
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