Which types of membrane channels can cause an IPSP on a neuron when acetylcholine binds to the receptor? Select all that apply.

A. Ionotropic ligand-gated channels
B. Leak channels
C. Metabotropic ligand-gated channels
D. Voltage-gated channels
E. Mechanically gated channels



Answer :

Final answer:

Ionotropic ligand-gated channels are crucial for generating an IPSP when acetylcholine binds, while metabotropic channels and voltage-gated channels play different roles in neuronal signaling.


Explanation:

Ionotropic ligand-gated channels are types of membrane channels that can cause an IPSP on a neuron when acetylcholine binds to the receptor. When acetylcholine binds to these receptors, they open and allow ion flow, leading to an inhibitory postsynaptic potential.

Metabotropic ligand-gated channels do not directly cause IPSPs when acetylcholine binds to the receptor. They are involved in slow and prolonged responses through intracellular signaling cascades.

Voltage-gated channels are not responsible for causing an IPSP when acetylcholine binds to the receptor. These channels are involved in generating and propagating action potentials in neurons.


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