Agonists increase neurotransmitter activity, antagonists block it; essential in pharmacological treatments.
Agonists are drugs that increase the activity of specific neurotransmitters, either by promoting their synthesis, reducing reuptake, or mimicking their effects at receptors.
For example, cocaine acts as an agonist for the neurotransmitter dopamine, resulting in pleasurable feelings similar to dopamine release. Conversely, an antagonist blocks or hinders a neurotransmitter's normal activity at the receptor sites.
Understanding the roles of agonists and antagonists is crucial in pharmacological treatments to correct neurotransmitter imbalances, such as in conditions like Parkinson's disease.
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