The newly hired nurse is monitoring a client for adverse reactions during barbiturate therapy. The nurse preceptor asks, "What is the major disadvantage of barbiturate use?" What is the best response by the newly hired nurse?

A. "There is poor absorption of the barbiturate."
B. "There is a potential for hepatotoxicity with barbiturates."
C. "Barbiturates have a prolonged half-life."
D. "There is a potential for drug dependence with barbiturates."



Answer :

Final answer:

Barbiturates pose a significant risk of drug dependence, potentially leading to aversive and life-threatening withdrawal experiences.


Explanation:

"There is a potential for drug dependence with barbiturates."

Barbiturates carry a major disadvantage of potential drug dependence. They have physical and psychological addiction potential, and abrupt withdrawal can lead to aversive and life-threatening experiences, especially for individuals with a long history of high doses. This highlights a significant drawback of barbiturate use in medical practice.

Drug dependence, along with the risk of overdose and potential interactions with other CNS depressants, underscores the challenges associated with the use of barbiturates despite their effectiveness as anxiolytics, hypnotics, and anticonvulsants.


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