Answered

Prior to administering an opioid, patients should be informed that the drug will:

A. increase neurotransmission, as these drugs prevent presynaptic [tex]Ca^{2+}[/tex] influx.
B. increase neurotransmission, as these drugs enhance presynaptic [tex]Ca^{2+}[/tex] influx.
C. decrease neurotransmission, as these drugs enhance presynaptic [tex]Ca^{2+}[/tex] influx.
D. decrease neurotransmission, as these drugs prevent presynaptic [tex]Ca^{2+}[/tex] influx.



Answer :

GinnyAnswer

Final answer:

Opioids decrease neurotransmission by preventing presynaptic Ca2+ influx.


Explanation:

Prior to administering an opioid, patients should be informed that the drug will:

  • Decrease neurotransmission, as these drugs prevent presynaptic Ca2+ influx.

When opioids interact with GABAergic neurons, they cause hyperpolarization and suppress the release of GABA onto dopaminergic VTA neurons, ultimately disinhibiting VTA neurons and increasing dopamine release onto downstream targets.


Learn more about Opioids and neurotransmission here:

https://brainly.com/question/37471672


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