Final answer:
Calcification is the process in which mineral salts, like hydroxyapatite, crystallize on the collagen fiber matrix in bones, leading to tissue hardening.
Explanation:
Calcification is the process by which mineral salts primarily including hydroxyapatite crystallize on the collagen fiber matrix of a growing bone, leading to its hardening and formation. Calcification occurs in the presence of collagen fibers, as they provide the necessary framework for the mineral salts to deposit and crystallize.
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