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Coumarins

How do coumarins prevent thrombus formation?

A. Work with other drug classes to decrease the thickness of blood
B. Break down the fibrin in clots
C. Directly impact platelet aggregation
D. Inhibit vitamin K-dependent clotting factors



Answer :

GinnyAnswer

Final answer:

Coumarins, like warfarin, prevent thrombus formation by inhibiting vitamin K-dependent clotting factors.


Explanation:

Coumarins, such as warfarin, prevent thrombus formation by inhibiting vitamin K-dependent clotting factors. They interfere with the action of vitamin K epoxide reductase, leading to less carboxylation of prothrombins and reduced blood clotting. This mechanism decreases the likelihood of thrombus formation.


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