Final answer:
Pyrogens are chemicals that induce fever as a defense mechanism in the body by altering the thermostat setting of the hypothalamus.
Explanation:
Pyrogens are chemicals that increase body temperature by causing blood vessels to constrict, inducing shivering, and stopping sweat glands from secreting fluid. When a bacterium is destroyed, endogenous pyrogens are released into the blood, resetting the body's thermostat to induce a fever as a defense mechanism. The hypothalamus plays a crucial role in regulating body temperature and responding to these pyrogens.
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