Answer :

Certainly! The expression to evaluate is [tex]\((3+3)(6)\)[/tex].

### Step-by-Step Solution:

1. First, let's solve the expression inside the parenthesis:
[tex]\[ 3 + 3 = \boxed{6} \][/tex]

2. Next, we need to multiply the result of the addition by 6:
[tex]\[ 6 \times 6 = \boxed{36} \][/tex]

So, the final result of the expression [tex]\((3+3)(6)\)[/tex] is [tex]\(\boxed{36}\)[/tex].

In addressing the other part of your question, here are three notable changes experienced from adolescence to adulthood, along with examples of the challenges associated with each:

### 1. Physical Changes
- Example of Challenge: Adolescents experience growth spurts and hormonal changes which can lead to issues such as acne, body image concerns, and can affect their self-esteem.

### 2. Emotional and Psychological Development
- Example of Challenge: As individuals transition from adolescence to adulthood, they often develop a more complex emotional understanding and deal with increased stress and anxiety related to future planning and decision-making.

### 3. Increased Responsibility
- Example of Challenge: With adulthood comes increased responsibilities such as managing finances, maintaining a job, and perhaps providing for a family, which can be overwhelming and lead to significant stress.