Final answer:
If kidneys fail to remove excess H+ ions, blood pH decreases causing acidosis, leading to reduced hemoglobin affinity for oxygen.
Explanation:
If the kidneys fail to remove excess H+ ions from the blood, the blood pH would decrease, leading to acidosis. This decrease in pH would result in a decrease in hemoglobin's affinity for oxygen because the increased H+ ions interfere with the binding of oxygen to hemoglobin, causing a rightward shift in the oxygen dissociation curve.
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