The Homestead Act greatly impacted the Indigenous People of the Great Plains by:

A. encouraging homesteaders to take over the Indigenous People's farms.
B. creating a drain on the food, clothing, and shelter of Indigenous People.
C. making new technologies available to Indigenous People.
D. bringing new schools to Indigenous settlements.

The Homestead Act of 1862 had a significant impact on the Indigenous People of the Great Plains, leading to land disruption, assimilation policies, and loss of communal practices.

Explanation:

The Homestead Act of 1862 greatly impacted the Indigenous People of the Great Plains by:

Encouraging Western migration and granting federal lands, disrupting Indigenous territories.
Implementing policies like the Dawes Act that aimed to assimilate Native Americans into mainstream society.
Resulting in the loss of communal lands and cultural practices for Native Americans.

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