In DIC, an increased D-dimer level is a characteristic lab finding indicating widespread clot breakdown.
Increased D-dimer is most consistent with disseminated intravascular coagulation (DIC) as it indicates increased clot breakdown due to widespread coagulation activation and fibrinolysis. Decreased fibrin split products would not align with DIC as they are products of fibrin degradation, which is increased in DIC. Thrombocytosis and increased fibrinogen levels are not typical findings in DIC. Conjugated hyperbilirubinemia is unrelated to DIC.
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