The gastroesophageal sphincter weakness can lead to conditions like heartburn and GERD due to stomach contents leaking back into the esophagus.
The weakness in the structure referred to in the question is the gastroesophageal sphincter. When this sphincter fails to close properly, it can result in stomach contents leaking back into the esophagus, leading to conditions like heartburn and gastroesophageal reflux disease (GERD). This malfunction of the gastroesophageal sphincter can cause damage to the esophageal membrane due to the highly acidic nature of stomach contents.
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