Final answer:
A mutation is a permanent alteration of the genetic sequence in an organism, resulting from damage to DNA or errors in replication, with variable observable effects.
Explanation:
A mutation is a permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA. Mutations result from damage to DNA which is not repaired, errors in the process of replication, or from the insertion or deletion of segments of DNA. Mutations may or may not produce discernible changes in the observable characteristics of an organism.
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