To travel from the Battle of Paris to the Battle of Orléans, you would need to head in a southeast direction. Paris is located to the north of Orléans, so when moving from Paris to Orléans, you would be traveling in a direction that is mostly south but slightly east.
Two cities that were first affected by the Black Death in 1350 were Constantinople and Caffa. The Black Death, a deadly pandemic caused by the bubonic plague, spread rapidly in the mid-14th century. Constantinople (modern-day Istanbul) in the Byzantine Empire and Caffa (in the Crimea region, now part of Ukraine) were among the first cities to experience the devastating impact of the Black Death in 1350.