Final answer:
After Prohibition, many Americans wanted to repeal the ban on alcohol due to its challenging consequences.
Explanation:
Repeal is the word that best fits the definition of what many Americans wanted after Prohibition was instated. Prohibition was the period in U.S. history when the production and sale of alcoholic beverages were banned by the 18th Amendment to the Constitution, leading to illegal activities like bootlegging. The desire for repeal grew due to the challenges and negative consequences associated with Prohibition.
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