Answer:
The supercoiling of a chromosome can affect DNA in several ways:Increased compaction: Supercoiling allows DNA to be packed into a small space within the cell, making it more compact and easier to manage.Accessibility: Supercoiled DNA has higher levels of accessibility, which means that it is more easily accessible to proteins and enzymes that need to interact with it in order to complete various processes.Transcription: Supercoiled DNA can affect the rate of transcription, the process by which the information encoded in DNA is used to synthesize RNA molecules.