Final answer:
In biology, antagonistic interactions between drugs occur when one drug decreases the toxic effect of another. A drug with a low therapeutic index is effective but has toxic side effects, while a drug with a high therapeutic index is safer.
Explanation:
Antagonistic interactions between drugs occur when one drug decreases the toxic effect of another. A drug that is effective but has toxic side effects is said to have a low therapeutic index, indicating a narrow margin of safety between the therapeutic and toxic doses. Conversely, a drug with a high therapeutic index is safer, as the ratio of the dose that produces toxicity to the dose for therapeutic response is larger.
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