A mutation of a portion of a DNA molecule changed the resulting mRNA sequence from AUU-GGG-UUC to CUU-GGG-UUC. Using the table below, predict the resulting amino acid sequence.

A. From Met-Gly-Leu to Leu-Gly-Phe
B. From Ile-Gly-Ser to Leu-Gly-Phe
C. From Ile-Gly-Phe to Leu-Gly-Phe
D. From Leu-Gly-Phe to Met-Gly-Leu



Answer :

Sure, let's break down the problem step by step.

1. Understand the question:
You've been given two sequences of mRNA before and after a mutation, and you need to predict the resulting amino acid sequences using a table that links mRNA codons to their corresponding amino acids.

2. Identify the original and mutated mRNA sequences:
- Original mRNA sequence: AUU-GGG-UUC
- Mutated mRNA sequence: CUU-GGG-UUC

3. Find the codons and their corresponding amino acids:
- mRNA codons are groups of three nucleotides that correspond to one amino acid each.
- We will find the amino acid each codon codes for using the genetic code table (The table itself is not provided here, so I am assuming knowledge of genetic codes):
- AUU codes for Isoleucine (Ile)
- GGG codes for Glycine (Gly)
- UUC codes for Phenylalanine (Phe)

Therefore, the original amino acid sequence is: Ile-Gly-Phe.

Now, let's translate the mutated mRNA sequence:
- CUU codes for Leucine (Leu)
- GGG codes for Glycine (Gly)
- UUC codes for Phenylalanine (Phe)

Therefore, the mutated amino acid sequence is: Leu-Gly-Phe.

4. Compare the amino acid sequences before and after the mutation:
- Original: Ile-Gly-Phe
- Mutated: Leu-Gly-Phe

5. Summarize the change:
The mutation changed the first amino acid from Isoleucine (Ile) to Leucine (Leu), while the rest of the amino acid sequence (Gly-Phe) remained the same.

So, the final answer describing the amino acid sequence change due to the mutation is:
The amino acid sequence changed from Isoleucine-Glycine-Phenylalanine (Ile-Gly-Phe) to Leucine-Glycine-Phenylalanine (Leu-Gly-Phe).