Answer :
Final answer:
Mutations in DNA are instrumental in cancer development and progression, influenced by environmental factors and genetic predispositions.
Explanation:
Mutations and cancer are closely related in the context of cancer development. Mutations in DNA play a significant role in the initiation and progression of cancer. Cancer cells often exhibit more genetic changes, including mutations, compared to normal cells.
One crucial aspect is that cancer causing mutations can be sporadic and induced by various environmental factors like radiation, viruses, and chemicals. These mutations can affect key genes such as oncogenes and tumor suppressor genes, leading to uncontrolled cell growth and division, hallmark traits of cancer.
Understanding the interplay between mutations and cancer provides insights into potential drug targets for treatments, such as the enzyme target Gleevec™. Identifying mutations associated with cancer risk underscores the importance of genetic testing for individuals with familial cancer history.
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