The central concept in serologic testing is antigen-antibody interaction, crucial for detecting exposure to pathogens through specific binding. Measuring changes in antibody titer over time aids in distinguishing infections and monitoring immune responses.
Antigen-antibody interaction is a central concept in serologic testing. This interaction forms the basis for many diagnostic tests to detect exposure to specific pathogens through the specificity of antigen-antibody binding.
Antibodies produced by the immune system bind specifically to antigens, leading to the formation of visible matrices in agglutination tests or quantification of antigen titer in assays like ELISA.
Measuring changes in antibody titer over time can help distinguish current infections from past ones and monitor the immune system's response to pathogens.
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