Final answer:
Hydrophilic hormones need transport proteins to affect target cells.
Explanation:
Hydrophilic hormones require transport proteins to stimulate metabolic activity in their target cells. These hormones cannot diffuse through the lipid bilayer of the cell membrane and must pass on their message to a receptor located at the surface of the cell, initiating a signaling cascade that is carried out by a molecule called a second messenger.
Learn more about Hormone signaling and receptors here:
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