Which anti-platelet drug is contraindicated in heart failure?

A. Cilostazol (Pletal)
B. Dipyridamole (Persantine)
C. Aspirin
D. Eptifibatide (Integrilin)
E. Clopidogrel (Plavix)



Answer :

Final answer:

Aspirin is contraindicated in heart failure patients due to its antiplatelet properties, as it may interfere with compensatory mechanisms and worsen the condition.


Explanation:

Aspirin is the anti-platelet drug that is contraindicated in heart failure. While aspirin is commonly used in preventing cardiovascular events, its use in heart failure patients can lead to adverse effects due to its mechanism of action.

In heart failure, aspirin's antiplatelet properties may interfere with the body's compensatory mechanisms, potentially worsening the condition by inhibiting the beneficial effects of certain substances like prostaglandins.

Contrary to other anti-platelet drugs like clopidogrel (Plavix) or dipyridamole (Persantine), which may be used in heart failure patients without the same level of concern, aspirin should be used cautiously or avoided in such cases.


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